An Intraoperative Beta−Probe for Cancer Surgery (Springer by Francesco Collamati

By Francesco Collamati

This thesis specializes in a unique radio-guided surgical procedure strategy for whole tumor resections. It describes all features of the intraoperative probe, in addition to checking out and simulation of the radical approach. The presentation develops the process from the preliminary notion to lifelike feasibility experiences which were the topic of a statement of the yankee Society of Nuclear drugs. only a yr after finishing this paintings, the strategy has now been verified for the 1st time on a meningioma sufferer, confirming all the predictions made during this thesis.

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1 Physics in FLUKA The strength of FLUKA is in its physical models: microscopic models are adopted whenever possible, consistency among all the reaction steps and/or reaction types is ensured, conservation laws are enforced at each step, and crosschecks between results and experimental data are done at single interaction level. As a result, final predictions are obtained with a minimal set of free parameters fixed for all energy, target and projectile combinations. Therefore results in complex cases, as well as properties and scaling laws, arise naturally from the underlying physical models, predictivity is provided where no experimental data are directly available, and correlations within interactions and among eventual shower components are preserved.

Neurovirol. 4, 227–236 (1998) 4. L. Dorward, O. Alberti, B. A. J. D. T. Thomas, Postimaging brain distortion: magnitude, correlates, and impact on neuronavigation. J. Neurosurg. 88(4), 656–662 (1998). 0656 5. A. R. C. Lim, Implementation and preliminary clinical experience with the use of ceiling mounted mobile high field intraoperative magnetic resonance imaging between two operating rooms. Acta Neurochir. Suppl. 109, 97–102 (2011) 6. M. van Dam, G. A. J. G. Pleijhuis, W. Kelder, A. S. G. J. van der Zee, J.

Ferrari, J. R. Sala). Even if every new generation of the code originates from the previous one, each new version represented not only an improvement of the existing program, but rather a quantum jump in the code physics, design and goals. In this sense, the name FLUKA has been preserved as a reminder of this historical development, even if the present code has pretty much nothing to do with the versions which were released before 1990. FLUKA is developed using the FORTRAN 77 language. A graphical user interface named Flair (FLUKA Advanced Interface) has been developed using Phython [3].

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